{"id":5418,"date":"2025-05-09T11:26:20","date_gmt":"2025-05-09T03:26:20","guid":{"rendered":"https:\/\/www.hi-tech-materials.com\/?post_type=product&#038;p=5418"},"modified":"2025-05-09T11:27:54","modified_gmt":"2025-05-09T03:27:54","slug":"carboxylated-fe%e2%82%83o%e2%82%84-nanoparticles-coproprecipitation-method","status":"publish","type":"product","link":"https:\/\/www.hi-tech-materials.com\/zh\/product\/carboxylated-fe%e2%82%83o%e2%82%84-nanoparticles-coproprecipitation-method","title":{"rendered":"Carboxylated Fe\u2083O\u2084 Nanoparticles (Coproprecipitation Method)"},"content":{"rendered":"<p><strong>Product Overview<\/strong><br \/>\nCarboxylated Fe\u2083O\u2084 nanoparticles (prepared by the coprecipitation method) are modified with DMSA (dimercaptosuccinic acid), transforming them into water-soluble nanoparticles with carboxyl groups. This modification enhances their hydrophilicity and biocompatibility, making them highly suitable for various biomedical applications. These nanoparticles are especially promising for targeted drug delivery, magnetic resonance imaging (MRI), and magnetic hyperthermia therapy (MHT).<\/p>\n<p><strong>Key Features<\/strong><\/p>\n<ul>\n<li><strong>High Surface Negative Charge<\/strong>: DMSA molecules form stable covalent bonds with the surface of Fe\u2083O\u2084 nanoparticles via their thiol groups, creating a thick molecular coating that imparts a strong negative surface charge to the nanoparticles.<\/li>\n<li><strong>Hydrophilicity<\/strong>: DMSA-modified Fe\u2083O\u2084 nanoparticles exhibit excellent hydrophilicity, maintaining stability across a wide range of pH values.<\/li>\n<li><strong>Stability and Dispersion<\/strong>: The DMSA modification ensures good dispersion and stability of the nanoparticles, making them ideal for biological applications.<\/li>\n<li><strong>Suitable for Biomolecule Conjugation<\/strong>: Due to the carboxyl groups on the surface, DMSA-modified Fe\u2083O\u2084 nanoparticles can be used for biomolecule conjugation and immobilization, facilitating the construction of nanoprobes for various applications.<\/li>\n<\/ul>\n<p><strong>Applications<\/strong><\/p>\n<ul>\n<li><strong>Biomedical Applications<\/strong>: Due to their excellent biocompatibility and stability, DMSA-modified Fe\u2083O\u2084 nanoparticles serve as ideal drug carriers for targeted drug delivery and as contrast agents for MRI.<\/li>\n<li><strong>Magnetic Hyperthermia Therapy (MHT)<\/strong>: Under the influence of an alternating magnetic field, DMSA-modified Fe\u2083O\u2084 nanoparticles convert magnetic energy into heat, making them suitable for magnetic hyperthermia treatments for tumors.<\/li>\n<li><strong>Gene Therapy<\/strong>: These nanoparticles can be used as gene carriers in gene transfection and gene therapy applications.<\/li>\n<li><strong>Materials Science<\/strong>: DMSA-modified Fe\u2083O\u2084 nanoparticles enhance the magnetic properties of composite materials and can be applied in the development of smart materials and sensors.<\/li>\n<li><strong>Biomolecule Conjugation<\/strong>: The carboxyl groups on the surface can be used to conjugate biomolecules, enabling the construction of nanoprobes for biological detection and analysis.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"[tp_attributes num_attributes=\"5\"]\n<div tabindex=\"0\" role=\"article\" data-tabster=\"{&quot;groupper&quot;:{&quot;tabbability&quot;:2},&quot;focusable&quot;:{}}\" data-content=\"ai-message\" aria-labelledby=\"qCjP5C64NhAdgRPyfetDd-author} qCjP5C64NhAdgRPyfetDd-content-0\">\n<div id=\"qCjP5C64NhAdgRPyfetDd-content-0\">\n<p>Carboxylated Fe\u2083O\u2084 nanoparticles, synthesized via coprecipitation, provide optimized surface functionalization, superior dispersion stability, and enhanced magnetic properties. Designed for biomedical and industrial applications, they ensure efficient conjugation, extended durability, and high adaptability.<\/p>\n<\/div>\n<\/div>","protected":false},"featured_media":5419,"comment_status":"open","ping_status":"closed","template":"","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false},"product_cat":[3723,3698,69],"product_tag":[4189,4005],"class_list":{"0":"post-5418","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-nano-iron-oxide-feo-feo","7":"product_cat-nano-metal-oxides","8":"product_cat-nanomaterials","9":"product_tag-carboxylated-feo-nanoparticles","10":"product_tag-high-performance-biocompatible-nanomaterials","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product\/5418","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/comments?post=5418"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/media\/5419"}],"wp:attachment":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/media?parent=5418"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product_cat?post=5418"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product_tag?post=5418"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}