{"id":5400,"date":"2025-05-09T11:10:28","date_gmt":"2025-05-09T03:10:28","guid":{"rendered":"https:\/\/www.hi-tech-materials.com\/?post_type=product&#038;p=5400"},"modified":"2025-05-09T11:11:38","modified_gmt":"2025-05-09T03:11:38","slug":"pei-modified-magnetic-fe%e2%82%83o%e2%82%84-nanoparticles","status":"publish","type":"product","link":"https:\/\/www.hi-tech-materials.com\/zh\/product\/pei-modified-magnetic-fe%e2%82%83o%e2%82%84-nanoparticles","title":{"rendered":"PEI-modified Magnetic Fe\u2083O\u2084 Nanoparticles"},"content":{"rendered":"<p><strong>Product Overview<\/strong><br \/>\nPEI-modified magnetic Fe\u2083O\u2084 nanoparticles are composite nanomaterials that combine the magnetic properties of Fe\u2083O\u2084 with the high density of amine groups from polyethyleneimine (PEI). The PEI modification imparts a high positive surface charge to the Fe\u2083O\u2084 nanoparticles, enhancing their interaction with negatively charged cell membranes and improving their dispersion in aqueous media. These modified nanoparticles are widely used in biomedical applications, particularly in magnetic resonance imaging (MRI) and drug delivery.<\/p>\n<p><strong>Key Features<\/strong><\/p>\n<ul>\n<li><strong>High Surface Charge<\/strong>: The high density of amine groups on PEI provides Fe\u2083O\u2084 nanoparticles with a significant positive surface charge, enhancing their stability in biological systems and promoting efficient cellular uptake.<\/li>\n<li><strong>Good Colloidal Stability<\/strong>: The PEI modification improves the dispersion of Fe\u2083O\u2084 nanoparticles in aqueous media, preventing aggregation and ensuring stable colloidal suspension.<\/li>\n<li><strong>MRI Contrast Enhancement<\/strong>: PEI-modified Fe\u2083O\u2084 nanoparticles serve as effective MRI contrast agents, improving imaging resolution and contrast for better disease detection.<\/li>\n<li><strong>Enhanced Cellular Uptake<\/strong>: Due to their surface characteristics, these nanoparticles are easily internalized by cells, facilitating drug delivery and gene transfection.<\/li>\n<li><strong>Suitable for Transfection Studies<\/strong>: The transfection capability of PEI makes the modified Fe\u2083O\u2084 nanoparticles ideal for DNA or RNA cell transfection research.<\/li>\n<\/ul>\n<p><strong>Applications<\/strong><\/p>\n<ul>\n<li><strong>Magnetic Resonance Imaging (MRI)<\/strong>: PEI-modified Fe\u2083O\u2084 nanoparticles can be used as MRI contrast agents to enhance image contrast and improve disease detection sensitivity.<\/li>\n<li><strong>Targeted Molecular Imaging<\/strong>: By functionalizing the surface of Fe\u2083O\u2084 nanoparticles with targeting molecules (such as FITC, folic acid, or hyaluronic acid), imaging specificity for certain cells or tissues can be enhanced.<\/li>\n<li><strong>Dual-modal or Multi-modal Imaging<\/strong>: Combining PEI-modified Fe\u2083O\u2084 nanoparticles with other imaging materials (such as gold nanoparticles) can create composite nanomaterials for MR\/CT dual-modal imaging.<\/li>\n<li><strong>Drug Delivery System<\/strong>: PEI\u2019s high density of amine groups can form stable complexes with drug molecules, and the magnetic properties of Fe\u2083O\u2084 enable targeted delivery and controlled release of therapeutic agents.<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"[tp_attributes num_attributes=\"5\"]\n<div tabindex=\"0\" role=\"article\" data-tabster=\"{&quot;groupper&quot;:{&quot;tabbability&quot;:2},&quot;focusable&quot;:{}}\" data-content=\"ai-message\" aria-labelledby=\"qCjP5C64NhAdgRPyfetDd-author} qCjP5C64NhAdgRPyfetDd-content-0\">\n<div id=\"qCjP5C64NhAdgRPyfetDd-content-0\">\n<p>PEI-modified magnetic Fe\u2083O\u2084 nanoparticles provide optimized surface functionalization, superior biocompatibility, and enhanced magnetic responsiveness. Designed for advanced biomedical applications, they ensure efficient conjugation, extended circulation stability, and high-performance adaptability.<\/p>\n<\/div>\n<\/div>","protected":false},"featured_media":5375,"comment_status":"open","ping_status":"closed","template":"","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false},"product_cat":[3723,3698,69],"product_tag":[4005,4175],"class_list":{"0":"post-5400","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-nano-iron-oxide-feo-feo","7":"product_cat-nano-metal-oxides","8":"product_cat-nanomaterials","9":"product_tag-high-performance-biocompatible-nanomaterials","10":"product_tag-pei-modified-magnetic-feo-nanoparticles","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product\/5400","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/comments?post=5400"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/media\/5375"}],"wp:attachment":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/media?parent=5400"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product_cat?post=5400"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product_tag?post=5400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}