{"id":5377,"date":"2025-05-09T10:44:24","date_gmt":"2025-05-09T02:44:24","guid":{"rendered":"https:\/\/www.hi-tech-materials.com\/?post_type=product&#038;p=5377"},"modified":"2025-05-09T10:45:26","modified_gmt":"2025-05-09T02:45:26","slug":"pegylated-fe%e2%82%83o%e2%82%84-nanoparticles-carboxyl-terminated","status":"publish","type":"product","link":"https:\/\/www.hi-tech-materials.com\/zh\/product\/pegylated-fe%e2%82%83o%e2%82%84-nanoparticles-carboxyl-terminated","title":{"rendered":"PEGylated Fe\u2083O\u2084 Nanoparticles (Carboxyl-Terminated)"},"content":{"rendered":"<p><strong>Product Overview<\/strong><br \/>\nPEGylated Fe\u2083O\u2084 nanoparticles (Carboxyl-Terminated) are synthesized by modifying oleic acid-coated Fe\u2083O\u2084 nanoparticles with PEG-carboxyl groups via a high-temperature pyrolysis method. This modification successfully transforms the nanoparticles from an oil phase to a water phase, expanding their applications in biomedicine. The modification imparts better biocompatibility, stability, and targeting capabilities to the nanoparticles.<\/p>\n<p><strong>Key Features<\/strong><\/p>\n<ul>\n<li><strong>Biocompatibility<\/strong>: PEG modification enhances nanoparticle biocompatibility, reducing immune responses, making them suitable for biomedical applications.<\/li>\n<li><strong>Long Circulation Time<\/strong>: The PEG modification extends the blood circulation time of nanoparticles, enhancing their passive targeting to tumor sites.<\/li>\n<li><strong>Multifunctionality<\/strong>: The PEG terminus contains multiple functional groups (such as methoxy, carboxyl, and amino groups), facilitating conjugation with targeting molecules (e.g., antibodies, aptamers, targeting peptides) to construct targeted nanoprobes.<\/li>\n<li><strong>Enhanced Imaging Contrast<\/strong>: In magnetic resonance imaging (MRI), PEGylated Fe\u2083O\u2084 nanoparticles provide significant contrast enhancement, improving imaging clarity.<\/li>\n<li><strong>Stability<\/strong>: PEG modification increases nanoparticle stability, reduces immune reactions, and enhances their effectiveness in biological systems.<\/li>\n<\/ul>\n<p><strong>Applications<\/strong><\/p>\n<ul>\n<li><strong>Drug Delivery System<\/strong>: By improving stability and blood circulation time, PEGylated Fe\u2083O\u2084 nanoparticles serve as ideal drug carriers for targeted drug delivery.<\/li>\n<li><strong>Magnetic Induction Tumor Hyperthermia (MHT)<\/strong>: Utilizing the heat generation properties of Fe\u2083O\u2084 nanoparticles in an alternating magnetic field, PEGylated Fe\u2083O\u2084 nanoparticles are used for tumor treatment.<\/li>\n<li><strong>Biosensing and Detection<\/strong>: These nanoparticles are used in biosensing applications to detect biomolecules or environmental pollutants.<\/li>\n<li><strong>Nanotheranostics<\/strong>: Combining diagnostic imaging and therapeutic functions, PEGylated Fe\u2083O\u2084 nanoparticles serve as image-guided therapeutic carriers for precision treatment.<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"[tp_attributes num_attributes=\"5\"]\n<div tabindex=\"0\" role=\"article\" data-tabster=\"{&quot;groupper&quot;:{&quot;tabbability&quot;:2},&quot;focusable&quot;:{}}\" data-content=\"ai-message\" aria-labelledby=\"qCjP5C64NhAdgRPyfetDd-author} qCjP5C64NhAdgRPyfetDd-content-0\">\n<div id=\"qCjP5C64NhAdgRPyfetDd-content-0\">\n<p>PEGylated Fe\u2083O\u2084 nanoparticles (carboxyl-terminated) provide optimized surface functionality, superior biocompatibility, and enhanced dispersion stability. Designed for advanced biomedical applications, they ensure efficient conjugation, extended circulation, and high-performance adaptability.<\/p>\n<\/div>\n<\/div>","protected":false},"featured_media":5375,"comment_status":"open","ping_status":"closed","template":"","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false},"product_cat":[3723,3698,69],"product_tag":[4005,4157],"class_list":{"0":"post-5377","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-nano-iron-oxide-feo-feo","7":"product_cat-nano-metal-oxides","8":"product_cat-nanomaterials","9":"product_tag-high-performance-biocompatible-nanomaterials","10":"product_tag-pegylated-feo-nanoparticles-carboxyl-terminated","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product\/5377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/comments?post=5377"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/media\/5375"}],"wp:attachment":[{"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/media?parent=5377"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product_cat?post=5377"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hi-tech-materials.com\/zh\/wp-json\/wp\/v2\/product_tag?post=5377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}