Protein A Magnetic Beads

Product Overview

Protein A Magnetic Beads are a biotechnological tool designed for immunoprecipitation experiments. These beads are coated with Protein A, a protein derived from Staphylococcus aureus, which specifically binds to the Fc region of IgG antibodies from various mammalian species. Typically made from superparamagnetic materials, these beads exhibit excellent magnetic properties, making them easy to separate during experiments. They are widely used in biomedical research for antibody purification, immunoprecipitation, and affinity chromatography.

Key Features

• High Affinity: Protein A Magnetic Beads specifically bind to the Fc region of various mammalian IgG antibodies, providing extremely high affinity for antibody binding experiments.
• Superparamagnetic: Made with superparamagnetic materials, these beads are rapidly magnetized and demagnetized under an external magnetic field, facilitating quick and efficient separation during experimental procedures.
• Low Non-Specific Binding: These beads are pre-blocked to minimize non-specific binding, ensuring higher specificity and reproducibility in experiments.
• High Capacity: Protein A Magnetic Beads have a high binding capacity, allowing them to capture large amounts of antibodies or antigens, making them suitable for large-scale experiments.

Applications

• Immunoprecipitation: Protein A Magnetic Beads are used to capture antibody-antigen complexes from cell lysates, followed by analysis techniques such as Western Blotting or mass spectrometry.
• Antibody Purification: These beads are ideal for purifying specific antibodies from complex samples by utilizing the strong affinity between Protein A and IgG, resulting in highly pure antibodies.
• Affinity Chromatography: Protein A Magnetic Beads serve as solid-phase carriers in affinity chromatography, used for the separation and purification of target proteins.