Carboxylated Magnetic Microspheres

Product Overview

Carboxylated Magnetic Microspheres are functionalized magnetic microspheres with a surface rich in carboxyl groups. Typically made from superparamagnetic materials like Fe₃O₄ combined with polymeric materials, these microspheres are well-suited for various biomedical applications. Their surface modification with carboxyl groups allows for efficient covalent bonding with a wide range of biomolecules, enhancing their functionality in molecular immobilization, immunochromatography, cell separation, and purification.

Key Features

• Superparamagnetism: Made with superparamagnetic materials such as Fe₃O₄, these microspheres exhibit excellent magnetic properties. They are easily magnetized under an external magnetic field and lose their magnetism once the field is removed, making them easy to handle and separate.
• High Surface Area: The nano- or micro-scale particle size provides a large surface area, ideal for immobilizing biomolecules and catalyzing reactions.
• Carboxyl Functional Groups: The surface is rich in carboxyl groups, enabling efficient covalent attachment of biomolecules such as antibodies, proteins, and enzymes, enhancing their functionality in biomedical applications.
• Good Biocompatibility: These microspheres are made from biocompatible materials, minimizing immune reactions and toxicity, making them suitable for a variety of in vitro and in vivo biomedical applications.
• Suspension Stability: They exhibit good stability in suspension, ensuring reliable performance under various experimental conditions.

Applications

• Immunochromatographic Detection: After antibody modification, these microspheres can be used in the construction of immunochromatographic strips, enabling rapid and sensitive biomolecular detection.
• Biomolecule Immobilization: Serve as a carrier for immobilizing enzymes and other biomolecules, widely used in biochemical reactions and separation processes.
• Cell Separation and Purification: Exploiting their superparamagnetism, these microspheres allow for quick cell separation under an external magnetic field, ideal for cell sorting and purification.
• Drug Delivery: Can be used as part of a targeted drug delivery system, facilitating the transport of drugs to specific cells or tissues.
• Magnetic Analytical Systems: In combination with immunochromatography and magnetic analysis techniques, they enable quantitative and rapid detection of biomarkers like human chorionic gonadotropin (hCG), cardiac troponin, and HIV virus.
• Biomedical Applications: These microspheres are excellent for high-specificity binding and separation in research fields like cell sorting and protein interaction studies.