Silica Hydroxyl-Functionalized Magnetic Beads for Nucleic Acid Extraction

Product Overview

Silica Hydroxyl-Functionalized Magnetic Beads are designed for efficient nucleic acid extraction and purification. These beads feature an Fe₃O₄ core for superparamagnetic properties, coated with a SiO₂ shell and surface-functionalized with hydroxyl (-OH) groups. This design ensures a high surface area and excellent adsorption characteristics, enabling efficient nucleic acid enrichment, extraction, and purification across various biological samples. They are widely applied in nucleic acid research and analysis.

Key Features

• Nanometer-Sized Spheres, Uniform Particle Size: High surface area enhances nucleic acid capture efficiency, ensuring thorough extraction and purification.
• Superparamagnetic: Rapidly responds to external magnetic fields, facilitating quick separation and ease of handling.
• High Throughput: Compatible with automated systems, improving workflow efficiency and reducing labor time.
• Excellent Reproducibility: Consistent performance with minimal batch-to-batch variation, ensuring reliable and reproducible experimental results.

Applications

• Nucleic Acid Extraction: Efficiently extract nucleic acids from a variety of biological samples (e.g., blood, cells, tissues) under high-salt or low-pH conditions for optimal separation.
• Nucleic Acid Purification and Sorting: Purify and size-select nucleic acid fragments through specific binding interactions.
• mRNA Isolation and Purification: Use Oligo(dT)-functionalized beads for isolating and purifying mRNA from total RNA samples.
• Target Capture Sequencing: Leverage magnetic beads for liquid-phase capture in high-throughput sequencing (NGS) workflows, targeting specific genomic regions.
• Immunoassays: Use as a carrier for antigen-antibody interactions, applicable in hormone, neurotransmitter, cytokine, and tumor-associated antigen detection.