Protein G Magnetic Beads

Product Overview

Protein G Magnetic Beads are high-performance affinity particles used in biomedical research, particularly for antibody purification and immunoprecipitation (IP) methods. These beads are coated with recombinant Protein G, a protein that specifically binds to the IgG antibodies of various mammalian species. With their unique affinity, Protein G Magnetic Beads are ideal for antibody separation and purification. Typically made from superparamagnetic materials, these beads allow for fast and efficient separation and recovery during experiments.

Key Features

• High Capacity: Protein G Magnetic Beads offer a high binding capacity, enabling effective use in large-scale experiments with minimal usage per run.
• Low Non-Specific Binding: Pre-blocked to significantly reduce non-specific binding, ensuring high purity and reliable results in experiments.
• Flexibility: The surface of Protein G Magnetic Beads contains multiple IgG binding domains, providing enhanced flexibility for use with various antibody types.

Applications

• Immunoprecipitation (IP) and Co-Immunoprecipitation (Co-IP): These beads are used to precipitate specific antibodies or their complexes from samples derived from species such as mice, humans, rabbits, cows, goats, and sheep.
• Antibody Purification: Ideal for purifying IgG antibodies from serum, cell culture supernatant, or ascitic fluid, suitable for various IgG subclasses.
• Chemical Cross-Linking: Protein G Magnetic Beads can be used with cross-linking agents to covalently bind antibodies, reducing contamination of IgG in IP/Co-IP experiments and enabling the creation of reusable immunoprecipitation beads.