new material
Carboxylated iron oxide nanoparticles provide optimized surface functionalization, superior biocompatibility, and enhanced dispersion stability. Designed for advanced biomedical and industrial applications, they ensure efficient conjugation, extended durability, and high-performance adaptability.
Product Overview
Carboxylated iron oxide nanoparticles (DMSA@Fe₂O₃) are modified with carboxyl (-COOH) functional groups on the surface, which enhance their negative surface charge, water solubility, and stability. This modification provides excellent biocompatibility, making these nanoparticles suitable for various biomedical applications. The functionalized nanoparticles not only improve stability in biological systems but also offer multiple chemical functionalization sites for the conjugation and immobilization of biomolecules. These properties make them ideal for drug delivery, molecular probe construction, and other related applications.
Key Features
- Surface Functionalization with Carboxyl Groups: The carboxylated surface offers additional chemical functionalization sites, facilitating biomolecule conjugation and immobilization.
- High Negative Surface Charge: The carboxyl group modification increases the negative surface charge, improving the nanoparticles' stability in biological systems.
- High Loading Capacity: Capable of carrying a high molecular load, making them suitable for drug delivery and molecular probe applications.
- Dispersion and Stability: Exhibits excellent dispersion and stability, enabling long-term storage and use.
Applications
- Biomolecule Conjugation: The carboxylated surface allows these nanoparticles to couple with various biomolecules, facilitating the construction of molecular probes.
- Immobilization: With a high surface area and loading capacity, these nanoparticles can immobilize enzymes, antibodies, and other biomolecules, useful for biocatalysis and immunoassays.
- Magnetic Resonance Imaging (MRI) Contrast Agents: Due to their excellent magnetic properties, these nanoparticles are well-suited for use as MRI contrast agents, enhancing imaging contrast, particularly in animal studies.
- Drug Delivery: With their biocompatibility and magnetic properties, they can be used in targeted drug delivery systems, reducing side effects and enhancing therapeutic efficacy.
| Technical Parameter | Description |
| Form | Brown-clear aqueous colloid |
| Particle Diameter | ~10 nm |
| Concentration | 4 mg/mL |
| Notes | Magnetic separation columns are required for separation. |
