Biotin-Modified Magnetic Beads

Product Overview
Biotin-modified magnetic beads are products where biotin molecules are covalently coupled to superparamagnetic nanoparticles. These magnetic beads can rapidly, efficiently, and specifically bind to streptavidin or avidin, as well as antibodies, nucleic acids, proteins, and other molecules that are conjugated with these proteins. The beads are widely used for the separation, purification, and enrichment of target molecules that are conjugated with streptavidin or avidin. With high efficiency and sensitivity, these beads are extensively used in immunoprecipitation, cell sorting, DNA-protein interaction studies, and more.

Key Features

• High Binding Capacity: Offers fast and efficient separation and purification, effectively capturing target molecules.
• Strong Specificity: Specifically binds to molecules conjugated with streptavidin or avidin, ensuring high selectivity.
• Fast Binding Speed: With a large surface area, these beads significantly reduce the time required for molecular binding, improving work efficiency.

Applications

• Biomedical Research: Used in proteomics for protein separation, purification, and enrichment, enhancing protein yield and purity; in genomics for isolating and enriching gene fragments, providing high-quality materials for gene analysis and editing; in immunoassays for specific capture and separation of target molecules.
• Biotechnology: As drug carriers, these beads can target drug delivery to diseased areas, improving therapeutic efficacy while reducing side effects; used in biosensor construction based on the biotin-streptavidin system for detecting biomolecules, ions, and cells.
• Molecular Biology: Widely applied in next-generation sequencing, PCR, qPCR, droplet digital PCR, gene typing, and protein purification.
• Nucleic Acid Extraction: Used for nucleic acid purification through magnetic beads, allowing for simple buffer conditions to facilitate binding and extraction.
• Protein Purification: Magnetic beads bind specifically to target proteins under the influence of a magnetic field, enabling efficient protein separation and purification.
• Chemiluminescence and Biosensing: Used as fluorescent markers and detection carriers, enhancing detection sensitivity and specificity.
• Cell Sorting: In cell biology research, magnetic beads are used for the efficient sorting of specific cell subpopulations.