Ultra-Small Magnetic Fe₃O₄ Nanoparticles

Product Overview
Ultra-small magnetic Fe₃O₄ nanoparticles are a type of nanomaterial with an extremely small size, typically less than 10 nanometers, made from Fe₃O₄ (iron oxide). These nanoparticles exhibit superparamagnetic properties and excellent biocompatibility, making them suitable for biomedical applications, particularly in magnetic resonance imaging (MRI), magnetic hyperthermia (MHT), and drug delivery. Due to their ultra-small size, these nanoparticles show good diffusion and cell uptake capabilities, and they can be used in multimodal imaging and tumor synergistic therapy.

Key Features

• Ultra-Small Size: With a particle size typically in the range of 5-10 nm, these nanoparticles enhance diffusion within biological systems and improve cellular uptake efficiency.
• Superparamagnetism: These nanoparticles have high saturation magnetization, making them ideal for MRI and MHT applications.
• Size Effects: The ultra-small size gives Fe₃O₄ nanoparticles unique electronic structure and optical properties, allowing for better control of their magnetic properties and chemical reactivity compared to bulk materials.
• Biocompatibility and Biodegradability: Fe₃O₄ is biocompatible and can be metabolized and degraded in the body, offering significant potential for biomedical applications.

Applications

• MRI Contrast Agent: Ultra-small Fe₃O₄ nanoparticles can be used as T2 contrast agents for MRI, improving image clarity and accuracy, particularly for tumor imaging. Surface modification can further enhance their biocompatibility and tumor-targeting properties, boosting MRI signal and therapeutic efficacy.
• Magnetic Hyperthermia (MHT): In an alternating magnetic field, Fe₃O₄ nanoparticles generate localized heat, making them suitable for tumor treatment through magnetic hyperthermia. Surface modifications can increase nanoparticle accumulation at tumor sites, improving therapeutic outcomes.
• Drug Delivery System: As drug carriers, Fe₃O₄ nanoparticles can accumulate in tumor tissue through the enhanced permeability and retention (EPR) effect, improving targeted drug delivery efficiency.
• Multimodal Imaging and Tumor Synergistic Therapy: Fe₃O₄ nanoparticles and their composite materials are widely used in multimodal imaging and tumor synergistic therapy. Surface modification can enhance biocompatibility and tumor targeting, making them effective for integrated imaging and treatment.